Same here on the Octavia IV that I received in september 2021.
Some preferences are stored
Air conditioning settings
Radio favourites
Active user
A lot of preferences are not stored
Driving mode (always returns to 'normal'; this however may be a feature since I read in the manual or somewhere)
Headlight (always returns to 'auto'; I prefer always on)
Navigation settings (roadsigns, north-up, home, work, favourites, etc)
Assist settings (always return to all on)
The sceen I left on previous ride (always starts in home)
...
I went to the dealer. They said they executed an update (no effect visible in system info). They requested: 'See if your problem is solved'. Unfortunatelly it was not solved.
Only hope is that Skoda solves the stuff in next update :-(