Just picked up my second Karoq Edition so the handover was straightforward as I was familiar with most of the controls.
If you haven't had a VW or Skoda before get them to explain the controls and show you how the rear seat adjustment, movement, tipping and folding works.
Get them to explain Skoda Connect, it's free for the first year so make the most of it, and also the emergency call system, just don't press the red button!
Check that it has a spare wheel if you ordered one.
Make sure that the light switch is set to Auto.
Take some time to get the driver's seat right and understand what each seat adjustment does, they are not entirely logical.
I'd wait to try and understand the infotainment system once you get home and you have the time to sit and play with it.
One thing I will say is that the 2021 car drives a lot smoother and better than my 2018 car.