I am looking into (or attempting) making my Fabia 1 vRS sound a bit nicer. Anyone have any info on what exhausts have the nicest sound (despite it being diesel). Is it as simple as a back box delete ot should I get a full new exhaust system?

An old 2.2 Carlton I had many moons ago sounded great with the back box removed.

Change the engine for a high-revving petrol engine, otherwise it'll just sound like a loud tractor, BWAAARRRRR!!!!

The problem (if you can call it that) is that turbo diesel exhausts are quiet. Diesels themselves aren't that noisy but then adding the turbo quitens it still further. Most of the noise from the engine is the clatter from the high pressure rail fuel pump. 

 

So so you can stick almost any exhaust on a vRS and you won't get any more noise. You might get a slightly different noise, but it won't be any louder. If you just want a nice noise, Kufatec and Active-Sound make speaker kits for the vRS so it can sound like anything from a straight four petrol to a V12 Lamborghini. But some of the configurations are getting on for the price of a complete vRS.